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Title:
2,4−ジクロロ−a−(3,4−ジヒドロ−4−オキソ−2(1H)−キナゾリニリデン)−β−オキソ−ベンゼンプロパンニトリルを含むメラニン増進用組成物
Document Type and Number:
Japanese Patent JP6952104
Kind Code:
B2
Abstract:
One aspect of the present invention relates to a composition containing, as an active ingredient, 2,4-dichloro-a-(3,4-dirydro-4-oxo-2(1H)-quinazolinylidene)-β-oxo- benzenepropanenitrile, optical or stereoscopic isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof, or solvates thereof, for darkening hair color, preventing hair discoloration, and the prevention and treatment of melanin-reducing disease. According to the one aspect of the present invention, a novel use and effect of the 2,4-dichloro-a-(3,4-dirydro-4-oxo-2(1H)-quinazolinylidene)-β-oxo- benzenepropanenitrile can be provided to consumers and related industries can be promoted.

Inventors:
Choi, Hyun Jung
Bae, Il Hong
Kim Hyonjun
Lee, Jin Jin
Lee, Taeyeon
Cho, Dong Hyun
Application Number:
JP2019504924A
Publication Date:
October 20, 2021
Filing Date:
August 29, 2017
Export Citation:
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Assignee:
AMOREPACIFIC CORPORATION
International Classes:
A61K31/517; A61K8/49; A61P17/00; A61P43/00; A61Q5/10; A61Q19/00
Domestic Patent References:
JP2014506565A
Foreign References:
US20110015201
Other References:
Nature,2012年,Vol.484,No.7392,p.125-129
PLoS One,2016年12月,Vol.11,No.12,Article No.e0168025,p.1-13
Attorney, Agent or Firm:
Patent business corporation Yuko patent office