Title:
アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法
Document Type and Number:
Japanese Patent JP6975641
Kind Code:
B2
Abstract:
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia, using such dsRNA compositions.
Inventors:
William Courbes
Kevin Fitzgerald
James Butler
Stephanie williams
Gregory Hinkle
Martin Meier
Kevin Fitzgerald
James Butler
Stephanie williams
Gregory Hinkle
Martin Meier
Application Number:
JP2017553347A
Publication Date:
December 01, 2021
Filing Date:
April 13, 2016
Export Citation:
Assignee:
ALNYLAM PHARMACEUTICALS, INC.
International Classes:
C12N15/113; A61K31/712; A61K31/713; A61P3/06; C12N1/15; C12N1/19; C12N1/21; C12N5/10
Domestic Patent References:
| JP2014524738A | ||||
| JP2015502931A |
Foreign References:
| WO2014182661A2 |
Attorney, Agent or Firm:
Norihito Yamao
Kenji Tomita
Fumio Inai
Manami Sasakura
Kenji Tomita
Fumio Inai
Manami Sasakura