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Title:
アカルボースおよびメトホルミンの固定用量組合せ錠剤製剤およびその製造方法
Document Type and Number:
Japanese Patent JP7346404
Kind Code:
B2
Abstract:
The present invention is related to a fixed dose combination tablet formulation comprising the glycosidase inhibitor acarbose (0-4,6-Didesoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl] amino}-a-D-glucopyranosyl-(1,4)-0-a-D-glucopyranosyl-(1,4)-D-glucopyranose) and the glycerin-3-phosphate-Dehydrogenase inhibitor metformin (1,1-Dimethylbiguanid), particularly the hydrochloride salt of metformin. Also provided are processes for producing a fixed dose combination tablet formulation.

Inventors:
Annah, Johanna
Application Number:
JP2020528424A
Publication Date:
September 19, 2023
Filing Date:
December 18, 2018
Export Citation:
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Assignee:
Bayer Actien Gezershyaft
International Classes:
A61K31/7034; A61K9/20; A61K9/30; A61K31/155; A61K47/02; A61K47/04; A61K47/10; A61K47/12; A61K47/32; A61K47/38; A61P3/10
Domestic Patent References:
JP2013510875A
JP2008533127A
Foreign References:
WO2009135951A1
WO2004110422A1
WO2013115742A1
Attorney, Agent or Firm:
Makoto Ono
Kennori Kanayama
Yoshiyuki Tsubokura
Kazuki Shigemori
Kenji Ando
Hidehiko Ichikawa
Yoshie Sakurada
Yosuke Kawasaki
Takuya Gomibuchi
Toshikazu Imato
Youichi Iino
Yusuke Ichikawa
Masahiro Moriyama
Takashi Kawano
Yoshikazu Iwase
Yasufumi Shiroyama