Title:
Ｔｏｘｉｃ ＡＧＥｓ生成抑制剤
Document Type and Number:
Japanese Patent JP7398207
Kind Code:
B2
Abstract:
To provide an inhibitor capable of inhibiting formation of toxic AGEs (advanced glycation end-products formed through protein saccharification reaction).SOLUTION: An inhibitor of toxic AGEs formation contains quercetin glycoside represented by the chemical formula shown below. In the formula, R1 and R2 each independently represent a saccharide-derived structure.SELECTED DRAWING: None
Inventors:
Masataka Nakano
Thanja Mahamadou
Thanja Mahamadou
Application Number:
JP2019094423A
Publication Date:
December 14, 2023
Filing Date:
May 20, 2019
Export Citation:
Assignee:
Toyo Sugar Co., Ltd.
International Classes:
A61K31/7048; A23L33/10; A61K8/60; A61P3/10; A61P17/00; A61P43/00
Domestic Patent References:
| JP2017145236A | ||||
| JP2017057163A | ||||
| JP2019043952A | ||||
| JP2004059522A | ||||
| JP2014094966A |
Foreign References:
| WO2015083554A1 | ||||
| CN104000813A | ||||
| KR1020080013496A | ||||
| DE1302712B |
Other References:
糖化ストレスとアンチエイジング:10.糖化ストレスと肝疾患,Glycative Stress Research[オンライン],2018年,5(4),pp. 177-180
Takashi NAGASAWA et al.,Suppression of early and advanced glycation by dietary water-soluble rutin derivative in diabetic rats,International Congress Series,2002年11月,Vol. 1245,pp.403-405,DOI:10.1016/S0531-5131(02)00949-4
Takashi NAGASAWA et al.,Inhibition of glycation reaction in tissue protein incubations by water soluble rutin derivative,Molecularand Cellular Biochemistry,2003年,Vol. 249、No. 1/2,pp.3-10,DOI: 10.1023/A:1024793429244
Chi-Hao WU et al.,Inhibitory Effect of Naturally Occurring Flavonoids on the Formation of Advanced Glycation Endproducts,Journal of Agricultural and Food Chemistry,2005年03月25日,Vol. 53, No. 8,pp. 3167-3173,DOI:10.1021/jf048550u
Takashi NAGASAWA et al.,Dietary G-rutin suppresses glycation in tissue proteins of streptozotocin-induced diabetic rats,Molecular and Cellular Biochemistry,Vol. 252, No. 1/2,2003年,pp.141-147
Hiroaki MURAMOTO et al.,Serum levels of advanced glycation end-products (AGEs) in dialysis patients,Nihon Toseki Igakkai Zasshi,2013年,Vol. 46, No. 5,pp.467-473,DOI: doi.org/10.4009/jsdt.46.467
Takashi NAGASAWA et al.,Suppression of early and advanced glycation by dietary water-soluble rutin derivative in diabetic rats,International Congress Series,2002年11月,Vol. 1245,pp.403-405,DOI:10.1016/S0531-5131(02)00949-4
Takashi NAGASAWA et al.,Inhibition of glycation reaction in tissue protein incubations by water soluble rutin derivative,Molecularand Cellular Biochemistry,2003年,Vol. 249、No. 1/2,pp.3-10,DOI: 10.1023/A:1024793429244
Chi-Hao WU et al.,Inhibitory Effect of Naturally Occurring Flavonoids on the Formation of Advanced Glycation Endproducts,Journal of Agricultural and Food Chemistry,2005年03月25日,Vol. 53, No. 8,pp. 3167-3173,DOI:10.1021/jf048550u
Takashi NAGASAWA et al.,Dietary G-rutin suppresses glycation in tissue proteins of streptozotocin-induced diabetic rats,Molecular and Cellular Biochemistry,Vol. 252, No. 1/2,2003年,pp.141-147
Hiroaki MURAMOTO et al.,Serum levels of advanced glycation end-products (AGEs) in dialysis patients,Nihon Toseki Igakkai Zasshi,2013年,Vol. 46, No. 5,pp.467-473,DOI: doi.org/10.4009/jsdt.46.467
Attorney, Agent or Firm:
Patent Attorney Corporation SS International Patent Office