Document Type and Number:
Japanese Patent JPH0128746
Kind Code:
B2
Abstract:
Novel compounds having vasodilation and hypotensive effects are represented by the formula (I) where R1 is halogen, nitro, cyano or lower alkoxy; each of R2 and R3 is lower alkyl, lower haloalkyl, lower alkoxyalkyl, aralkyloxyalkyl, aryloxyalkyl, lower alkenoxyalkyl, N,N-di-lower alkylaminoalkyl, N-lower alkyl-N-aralkylaminoalkyl, piperidylalkyl, 4-lower alkyl piperazinylalkyl, norpholinoalkyl or 1-pyrrolidinylalkyl; R4 is lower alkyl; A is lower alkylene; and R5 is hydrogen, lower alkyl, cycloalkyl of 3 to 7 carbon atoms, or aryl unsubstituted or substituted by one or two substituents selected from halogen, nitro, lower alkyl, lower alkoxy, di-lower alkylamino and cyano. Also disclosed are processes for their preparation.
Inventors:
MYANO TETSUJI
SUZUKI KUNIO
HARADA NOBUO
SUZUKI KUNIO
HARADA NOBUO
Application Number:
JP6067781A
Publication Date:
June 05, 1989
Filing Date:
April 23, 1981
Export Citation:
Assignee:
BANYU PHARMA CO LTD
International Classes:
A61K31/4418; A61K31/4422; A61K31/445; A61K31/455; A61K31/495; A61K31/54; A61P9/08; A61P9/10; A61P9/12; C07D211/90; C07D401/12; C07D413/12
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