Document Type and Number:
Japanese Patent JPH0132835
Kind Code:
B2
Abstract:
The nicotinic derivatives of glucosamine, particularly N-nicotinoyl-glucosamine tetranicotinate are described as having anti-lipolitic, hypocholesterolemizing and antiaterogenic activities, at an equal or higher level than those of nicotinic acid, without the objectionable side effects shown by the acid. To prepare the compounds of the invention, nicotinoyl chloride hydrochloride and glucosamine hydrochloride are reacted in an organic solvent at a temperature of between 40 DEG C. and 120 DEG C.
Inventors:
UORUTAA MURUMAN
OSUGUARUDO HONKIRORI
OSUGUARUDO HONKIRORI
Application Number:
JP7640781A
Publication Date:
July 10, 1989
Filing Date:
May 20, 1981
Export Citation:
Assignee:
RABO* GUIDOCHI E CO SPA
International Classes:
A61K31/70; A61K31/7024; A61P3/06; C07H13/10
Next Patent: JPH0132836