Document Type and Number:
Japanese Patent JPH0142955
Kind Code:
B2
Abstract:
A 7-[2-(2-aminothiazol-4-yl)-2- (syn)-alkoxy- iminoacetamido]cephalosporin derivative of the formula: wherein R3 represents -CH2R5 (R5 is a hydrogen atom or the residue of a nucleophilic compound), a halogen atom, an alkoxyl group, thiol group, amino group or (Z is hydrogen atom or hydroxyl, amino, thiol or a hydrocarbon group which may be substituted), -COOR4 represents a carboxylic group which may be esterified and R6 represents an alkyl group, or a salt thereof is prepared by reacting a novel 7-(4-halogeno-3-oxo-2- alkoxyiminobutyrylamino) cephalosporin derivative of the formula: wherein X represents a halogen atom and other symbols have the same meanings as defined above, or a salt thereof with thiourea; the halo reactant is made by acylating the corresponding 7-amino-cephalosporin.
Inventors:
OCHIAI MICHIHIKO
MORIMOTO AKIRA
OKADA TAIICHI
MORIMOTO AKIRA
OKADA TAIICHI
Application Number:
JP303278A
Publication Date:
September 18, 1989
Filing Date:
January 13, 1978
Export Citation:
Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
A61K31/545; A61K31/546; A61P31/04; C07C67/00; C07C239/00; C07C251/34; C07D501/20; C07D501/22; C07D501/24; C07D501/28; C07D501/36; C07D501/38; C07D501/59; A61K
Next Patent: JPH0142956