Title:
【発明の名称】酸性化された細胞内小胞内で開裂可能な蛋白質架橋試薬
Document Type and Number:
Japanese Patent JPH03502098
Kind Code:
A
Abstract:
Crosslinking reagents for amino group-containing compounds are provided, which crosslinkers can be cleaved under mildly acidic conditions. The crosslinkers can be used to crosslink biologically active substances to be delivered to the cells, wherein the crosslinker will be cleaved in the mildly acidic conditions within the cell.
Inventors:
Nevire, Jr., David M.
Sriniva Sacher, Katsuri
Sriniva Sacher, Katsuri
Application Number:
JP50658989A
Publication Date:
May 16, 1991
Filing Date:
May 31, 1989
Export Citation:
Assignee:
US HEALTH (US)
International Classes:
A61K31/70; A61K31/785; A61K39/395; A61K45/00; A61K47/48; A61P31/12; C07D207/452; C07D207/456; C07D493/10; C07K1/00; C07K14/00; C07K14/575; C07K14/62; C07K16/00; C07D207/44; (IPC1-7): A61K31/70; A61K31/785; A61K39/395; A61K45/00; C07D207/452; C07D493/10; C07K3/00; C07K15/12
Domestic Patent References:
| JPS6345561A | 1988-02-26 | |||
| JPS62500100A | 1987-01-16 |
Attorney, Agent or Firm:
Yumi Kaida (2 outside)
Previous Patent: ポリエステルとアルキルヒドロキシ（メタ）アクリレート化合物とのブレ...
Next Patent: 疾患の予防および治療のための酸化防止剤として有用な合成触媒のフリー...
Next Patent: 疾患の予防および治療のための酸化防止剤として有用な合成触媒のフリー...