Document Type and Number:
Japanese Patent JPH0421667
Kind Code:
B2
Abstract:
Novel 1,5-benzothiazepine derivatives of the formula: wherein R<1> is hydrogen or lower alkanoyl, each of R<2> and R<3> is lower alkyl, and either one of R<4> and R<5> is fluorine and the other one is hydrogen, and a pharmaceutically acceptable acid addition salt thereof, the derivative (I) and its salt being useful as a hypotensive agent and/or a cerebral or coronary vasodilator, and a 1,5 benzothiazepine derivative of the formula wherein R<1> is hydrogen or lower alkanoyl, and either one of R<4> and R<5> is fluorine and the other one is hydrogen, or a salt thereof.
Inventors:
TAKEDA MIKIO
OOISHI ATSUO
NAKAJIMA HIROMICHI
NAGAO HIROSHI
OOISHI ATSUO
NAKAJIMA HIROMICHI
NAGAO HIROSHI
Application Number:
JP2403985A
Publication Date:
April 13, 1992
Filing Date:
February 08, 1985
Export Citation:
Assignee:
TANABE SEIYAKU CO
International Classes:
A61K31/55; A61K31/554; A61P9/08; A61P9/10; A61P9/12; C07D281/10
Next Patent: JPH0421668