Title:
【発明の名称】グリコサミノグリカン塩、その製造方法およびそれを含有する医薬組成物
Document Type and Number:
Japanese Patent JPH04500377
Kind Code:
A
Abstract:
PCT No. PCT/EP89/00605 Sec. 371 Date Nov. 15, 1990 Sec. 102(e) Date Nov. 15, 1990 PCT Filed May 30, 1989 PCT Pub. No. WO90/12589 PCT Pub. Date Nov. 1, 1990.Salts of glycosaminoglycans (heparin, its fractions or fragments which are supersulfated, dermatan sulfate, heparan sulfate, and modified heparins) with bases of formula (I), (I) wherein R1, R2, R3, and R4 represent H, alkyl, or cycloalkyl; R5 and R6 represent H, or alkyl; R7 and R8 represent H or alkyl; n and m are integers from 1-4 and X is -O-CO-O-, which salts have the pharmacological properties of the glycosaminoglycans themselves, and are orally and rectally administrable.
Inventors:
Dar Pozzo Arma
Aqua Sariente Maurizio
Sportetti Giancarlo
Saleto Monique
Felti Paolo
De Santis Francesco
Aqua Sariente Maurizio
Sportetti Giancarlo
Saleto Monique
Felti Paolo
De Santis Francesco
Application Number:
JP50614189A
Publication Date:
January 23, 1992
Filing Date:
May 30, 1989
Export Citation:
Assignee:
ITALFARMACO SPA (IT)
International Classes:
C07C233/36; A61K31/715; A61P3/06; A61P7/02; C07C211/63; C07C219/02; C07C229/06; C07C237/00; C07C237/04; C07C237/10; C07C271/06; C07C271/20; C07C275/04; C07C275/14; C08B37/00; C08B37/10; A61K; C07C; C08B; (IPC1-7): A61K31/725; C07C211/63; C07C219/02; C07C229/06; C07C237/10; C07C271/20; C07C275/14; C08B37/10
Attorney, Agent or Firm:
Michiko Shinoda (1 outside)