Title:
【発明の名称】リポキシゲナーゼ阻止化合物
Document Type and Number:
Japanese Patent JPH04503074
Kind Code:
A
Abstract:
Certain N-aryl-, N-heteroaryl-, N-arylalkyl-, N-heteroarylalkyl-, N-arylcyclopropyl- and N-heteroaryl-cyclopropyl-N'-hydroxyurea compounds are inhibitors of lipoxygenase enzyme activity and are thus useful agents in treating disease states such as asthma, arthritis, allergy, psoriasis, inflammatory bowel disease, gout, adult respiratory distress syndrome, endotoxin shock, and other inflammatory conditions in which the products of the arachidonic acid cascade are implicated.
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Inventors:
Brox, Day Doubler
Karen Yee, Rodricos
Summers, The Ames Bee
Karen Yee, Rodricos
Summers, The Ames Bee
Application Number:
JP50369390A
Publication Date:
June 04, 1992
Filing Date:
January 25, 1990
Export Citation:
Assignee:
Abbot Laboratories
International Classes:
A61K31/17; A61K31/215; A61K31/34; A61K31/341; A61K31/343; A61K31/38; A61K31/381; A61K31/40; A61K31/403; A61K31/404; A61P37/06; A61P43/00; C07C275/64; C07D207/09; C07D209/14; C07D213/30; C07D213/68; C07D307/42; C07D307/52; C07D307/81; C07D333/16; C07D333/20; C07D333/32; C07D333/56; C07D333/58; C07D333/64; C07D405/04; C07D405/06; C07D409/04; C07D409/06; (IPC1-7): A61K31/17; A61K31/215; A61K31/34; A61K31/38; A61K31/40; C07C275/64; C07D207/09; C07D209/14; C07D307/52; C07D307/81; C07D333/20; C07D405/04; C07D409/04
Attorney, Agent or Firm:
Yoshio Kawaguchi (4 outside)