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Document Type and Number:
Japanese Patent JPH0480889
Kind Code:
B2
Abstract:
A novel nitromethylation composition comprising nitromethane and a catalytic amount of a bifunctional basic catalyst, optionally in an organic solvent, a method of nitromethylating ketonic compounds with said compositions and novel steroids of the formulae I and I' wherein R1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms optionally substituted with an oxygen or nitrogen group or halogen and alkenyl and alkynyl of 2 to 4 carbon atoms, R2 is alkyl of 1 to 4 carbon atoms and the A,B,C and D rings optionally contain at least one double bond and optionally substituted with at least one member of the group consisting of -OH, =0, halogen, alkyl and alkoxy of 1 to 4 carbon atoms and alkenyl and alkynyl of 2 to 4 carbon atoms and their use to form the corresponding 21-acetoxy-20-ketocorticosteroids compounds in a simple manner.

Inventors:
DEREKU HARORUDO RICHAADO BAATON
UIRIAMU BURANKUSU MAZAUERU
SAMIIRU ZAARU ZAARU
Application Number:
JP2223183A
Publication Date:
December 21, 1992
Filing Date:
February 15, 1983
Export Citation:
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Assignee:
ROUSSEL UCLAF
International Classes:
C07B37/04; B01J31/00; B01J31/02; C07B31/00; C07B61/00; C07C67/00; C07C205/04; C07J5/00; C07J7/00; C07J9/00; C07J13/00; C07J41/00; C07J63/00