Title:
【発明の名称】1―ヒドロキシアルキル―5―ニトロイミダゾール類の製造方法
Document Type and Number:
Japanese Patent JPH05505187
Kind Code:
A
Abstract:
Process for preparing hydroxyalkyl-1 nitro-5 imidazoles of the general formula (I) by the action of an alkylene oxide on a complex of sulphuric anhydride with a derivative of imidazole of the general formula (II) followed by the acid hydrolysis or alcoholysis of the product obtained. In the general formulae (I) and (II), R is hydrogen, phenyalkyl or phenyl (possibly substitued). In the general formula (I), n is 2 or 3 and one or more carbon atoms of the alkylene chain may be substitued by one or more methyl radicals. In the general formula (II), X is a group which may be eliminated by acid hydrolysis or alcoholysis.
Inventors:
Ravigne, Michel
Mandal-Kazan, Bernadette
Mandal-Kazan, Bernadette
Application Number:
JP50579791A
Publication Date:
August 05, 1993
Filing Date:
March 11, 1991
Export Citation:
Assignee:
Loan-Poulin Lore Societe Anonym
International Classes:
C07D233/93; C07D233/94; C07D233/92; (IPC1-7): C07D233/92; C07D233/93
Attorney, Agent or Firm:
Heiyoshi Odashima