Title:
【発明の名称】N―アルキル―タウロウルソデオキシコール酸およびそれらの治療活性誘導体、それらの調製方法、ならびにそれらを含む医薬組成物
Document Type and Number:
Japanese Patent JPH05508168
Kind Code:
A
Abstract:
The N-alkyl-tauroursodeoxycholic acids of formula (I) and their pharmaceutically acceptable derivatives are useful in the therapy of hepatic diseases and troubles. For the preparation of these acids a conjugation reaction is effected between a mixed anhydride of ursodeoxycholic acid and alkyltaurine, the acide being then obtained by percolation through two columns respectively containing a strong cationic resin in H<+> form and a weakly anionic resin in OH<-> form. r
Inventors:
Massimo Parenti
Application Number:
JP50766592A
Publication Date:
November 18, 1993
Filing Date:
April 16, 1992
Export Citation:
Assignee:
Prodotti Kimichie Alimentary Societa Peratini
International Classes:
A61P1/00; A61P1/16; A61K31/575; C07J41/00; (IPC1-7): C07J41/00; A61K31/575
Attorney, Agent or Firm:
Yoshikazu Tani