Document Type and Number:
Japanese Patent JPH0555518
Kind Code:
B2
Abstract:
The invention relates to a novel diosmin derivative and to the preparation of this diosmin octakis(hydrogen sulphate)/aluminium complex by reacting diosmin with a sulphating agent such as the sulphur dioxide/pyridine complex, the sulphur trioxide/trimethylamine complex and the sulphur trioxide/triethylamine complex at a temperature between 40 and 110 degree C in a suitable medium, preferably pyridine, dimethylformamide and dimethylacetamide, and finally adding aluminium hydroxychloride.
Inventors:
AURERIO ORUHARESU BENERO
RAMON MOSUKEERA PESUTAANYA
RAMON MOSUKEERA PESUTAANYA
Application Number:
JP18953288A
Publication Date:
August 17, 1993
Filing Date:
July 28, 1988
Export Citation:
Assignee:
FUABURIKA ESUPANYOORA DE PUROD
International Classes:
A61K31/70; A61K31/7042; A61K31/7048; A61P1/04; C07F5/06; C07H17/07; C07H23/00; C07F; C07H; (IPC1-7): C07H17/07; A61K31/70
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