Title:
【発明の名称】光学活性3―(メタンスルホニルオキシ)チオランおよびその類似化合物
Document Type and Number:
Japanese Patent JPH0637459
Kind Code:
B2
Abstract:
Intermediates and a stepwise process for the conversion of D-methionine or certain of its derivatives to optically active compounds of the formula wherein R is (C1-C3)alkyl, phenyl or tolyl. The latter compounds are in turn useful as an intermediate in the preparation of penem antibiotic 5R,6S-6-(1R-hydroxyethyl)-2-(1R-oxo-3S-thiola nylthio)-2-penem-3-carboxylic acid and corresponding pharmaceutically acceptable salts and esters.
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Inventors:
Frank John Urban
Application Number:
JP9990389A
Publication Date:
May 18, 1994
Filing Date:
April 19, 1989
Export Citation:
Assignee:
Pfizer Inc.
International Classes:
C07B61/00; C07C319/20; C07C323/23; C07C323/66; C07C333/32; C07D333/32; C07D333/46; C07D333/48; C07D499/88; C07C323/12; (IPC1-7): C07C323/23; C07D333/32; C07D333/46; C07D333/48
Attorney, Agent or Firm:
Kyozo Yuasa (4 outside)
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