Title:
置換イソキノリン誘導体および抗潰瘍剤
Document Type and Number:
Japanese Patent JPH064625
Kind Code:
B2
Abstract:
A compound of the formula : (wherein R is hydrogen, hydroxy, methoxy, acetoxy, acetoxymethyl or trifluoromethyl; R<1>, R<2>, R<3> and R<4> each is hydrogen, hydroxy, optionally substituted C1-C5 alkoxy, acetoxy, propynyloxy, allyloxy or benzyloxy; or R<2> and R<3> taken together form methylenedioxy; R<5> is hydrogen, hydroxymethyl, C2-C4 alkoxycarbonyl, C2-C5 acyloxymethyl or phthalidyl; and n is 0 or 1 except for the case in which R is methoxy and R<1>, R<2>, R<3>, R<4> and R<5> each is hydrogen) or its pharmaceutically acceptable acid addition salt, being useful as anti-ulcer agents is provided through several routes.
Inventors:
HIRAI KENTARO
MIZUSHIMA TAKAO
MIZUSHIMA TAKAO
Application Number:
JP16504487A
Publication Date:
January 19, 1994
Filing Date:
June 30, 1987
Export Citation:
Assignee:
SHIONOGI SEIYAKU KK
International Classes:
A61K31/415; A61K31/47; A61K31/472; A61P1/04; C07D217/16; C07D217/26; C07D401/12; C07D405/14; C07D491/04; C07D491/056; (IPC1-7): C07D401/12; A61K31/47; C07D405/14; C07D491/056
Attorney, Agent or Firm:
岩崎 光隆
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