Title:
【発明の名称】新しいヒト組み換えガンマ-インターフェロン
Document Type and Number:
Japanese Patent JPH06502992
Kind Code:
A
Abstract:
The invention concerns a new mutant of $g(g)-IFN. This new polypeptide contains 134 amino acids. Amino acids 1 to 132 are the same as those of natural $g(g)-interferon. The first amino acid, methionine, in the zero position is also present, as has been demonstrated by protein sequencing. The amino acid in position 133 is leucine instead of glutamine. The invention also concerns DNA sequences and plasmid DNA (DSM 6238) which codes for this new polypeptide. The invention further concerns the use of the polypeptide as a drug as well as its use as a fine-chemical reagent for $i(in vitro) experiments.
Inventors:
Srodowski, Otto
Beam, Joachim
Otto, Bernd
Beam, Joachim
Otto, Bernd
Application Number:
JP50025492A
Publication Date:
April 07, 1994
Filing Date:
November 14, 1991
Export Citation:
Assignee:
Fraunhofer-Gesellschaft Tour Velderung der Angevanten Forschung A. Fau.
International Classes:
A61P13/12; A61P29/00; A61P35/00; A61P43/00; C07K14/00; C07K14/52; C07K14/555; C07K14/57; C12N1/21; C12N15/09; A61K38/21; C12N15/23; C12P21/02; G01N33/53; A61K38/00; C12R1/19; (IPC1-7): C12P21/02; C12N15/23; C12N1/21; C07K13/00; C07K3/22; C07K3/18; A61K37/66
Attorney, Agent or Firm:
Shusaku Yamamoto