Title:
【発明の名称】重合体誘導体結合アンスラサイクリン配糖体を含有する医薬組成物及びその製造方法
Document Type and Number:
Japanese Patent JPH06505755
Kind Code:
A
Abstract:
A lyophilized composition comprising (a) a conjugate comprising a N-alkyl methacrylamide-based copolymer and an anthracycline glycoside linked through a peptide spacer to the copolymer and (b) a cosolubilizing agent may optionally also contain (c) a filler. Also optionally, a targeting moiety may be linked to the copolymer of the conjugate via a peptide spacer. An injectable solution of the conjugate is obtained by reconstitution of the lyophilized composition.
Inventors:
Adami, Marco
Roberto Maglini
Marangi, Paolo
Surat, Antonio
Roberto Maglini
Marangi, Paolo
Surat, Antonio
Application Number:
JP51210392A
Publication Date:
June 30, 1994
Filing Date:
December 21, 1992
Export Citation:
Assignee:
Farmacia e Appzyon Esset Pear
International Classes:
A61K9/00; A61K9/19; A61K31/7008; A61K31/704; A61K47/48; A61K47/10; A61K47/14; A61K47/26; (IPC1-7): A61K47/48
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)