Title:
【発明の名称】ベータラクタム抗生物質中間体
Document Type and Number:
Japanese Patent JPH0670006
Kind Code:
B2
Abstract:
Beta lactams (I) having an SO3M substit. at 1-position and an opt. substd. or protected amino gp. or azido gp. at the 3-position are new. (M is hydrogen or a cation). They can also be substd. at the 4-position by alkyl, cycloalkyl, opt. substd. phenyl, alkoxycarbonyl, alken-1-yl, alkyn-1-yl, 2-phenylethenyl or 2-phenylethynyl. (I) having a 3-acylamino substit. are antibacterials effective against Gram negative and positive species, and useful therapeutically in human or veterinary medicine. The other new cpds. are intermediates.
Inventors:
Richard Be Sykes
William El Parker
Christopher M. Simarasti
William Aitch Coster
William A. Sursearch
Alain W. Fritz
David M Floyd
William El Parker
Christopher M. Simarasti
William Aitch Coster
William A. Sursearch
Alain W. Fritz
David M Floyd
Application Number:
JP12125191A
Publication Date:
September 07, 1994
Filing Date:
May 27, 1991
Export Citation:
Assignee:
E.R. SQUIBB & SONS,INCORPORATED
International Classes:
A61K31/395; A61K31/397; A61K31/41; A61K31/42; A61K31/425; A61K31/435; A61P31/04; C07C67/00; C07C301/00; C07C303/34; C07C307/02; C07D205/08; C07D205/085; C07D213/18; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D417/12; C07D471/04; C07F7/08; C07F7/10; C07F9/6558; C12P17/10; (IPC1-7): C07D205/085; A61K31/395
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)