Title:
【発明の名称】CL‐1577‐B▲下4▼化合物およびその製法
Document Type and Number:
Japanese Patent JPH0689012
Kind Code:
B2
Abstract:
CL-1577-B, compound is derived by the solvolysis under anhydrous conditions of either CL-1577A compound or CL-1577B compound, obtained from the fermentative action of a purified strain of Actinomycete designated ATCC 39363 under aerobic conditions.CL-1577-B4 compound is a potent antimicrobial agent, possessing activity against a number of gram-positive and gram-negative bacteria, yeasts, and fungi. In addition, the compound exhibits in vivo activity against the P388 murine leukemia cell line and in vitro activity against the L1210 murine leukemia cell line.A method of making the compound as well as pharmaceutical compositions and methods for their use are also disclosed.
Inventors:
Jiyoung H. Wilton
The Errored Sea Houcanson
The Aims C French
The Errored Sea Houcanson
The Aims C French
Application Number:
JP5517886A
Publication Date:
November 09, 1994
Filing Date:
March 14, 1986
Export Citation:
Assignee:
Warner-Lambert Company
International Classes:
A61K35/74; A61P31/04; A61P35/00; C12N1/20; C12P1/06; C07G11/00; C12R1/01; C12R1/04; (IPC1-7): C07G11/00; A61K35/74; C12P1/06
Attorney, Agent or Firm:
Chika Takagi (2 outside)
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