Title:
【発明の名称】固定化したビオチン化受容体を用いるリガンド測定のための試験装置,キットおよび方法
Document Type and Number:
Japanese Patent JPH0731206
Kind Code:
B2
Abstract:
A device useful for the determination of a ligand in an aqueous liquid comprises a water-insoluble substrate. Immobilized in at least one location on that substrate is a biotinylated receptor for the ligand. This receptor is in dried form and immobilized with one or more dried water-soluble acrylamide homo- or copolymer binder materials. When the immobilized receptor is contacted with an aqueous sample, the binder material is dissolved and the receptor is released for reaction with the ligand. The resulting reaction product is determined in a suitable manner. The device can be included in a kit having other components useful for ligand determination. The device and method of its use are particularly useful for the determination of human chorionic gonadotropin (hCG) as an early indicator of pregnancy.
Inventors:
Margaret Janet Smith-Lewis
Application Number:
JP31653788A
Publication Date:
April 10, 1995
Filing Date:
December 16, 1988
Export Citation:
Assignee:
Eastman Kodak Company
International Classes:
G01N33/53; C12M1/34; G01N33/543; G01N33/545; G01N33/76; (IPC1-7): G01N33/543
Domestic Patent References:
| JP62162964A |
Attorney, Agent or Firm:
Aoki Akira (4 outside)
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