Title:
【発明の名称】PAFの拮抗剤としての4-(1H-2-メチルイミダゾ〔4,5-c〕ピリジニルメチル)フェニルスルホンアミド誘導体
Document Type and Number:
Japanese Patent JPH07503954
Kind Code:
A
Abstract:
PCT No. PCT/GB93/00273 Sec. 371 Date Oct. 27, 1994 Sec. 102(e) Date Oct. 27, 1994 PCT Filed Feb. 10, 1993 PCT Pub. No. WO93/16075 PCT Pub. Date Aug. 19, 1993.The present invention is directed to compounds of general formula I as well their pharmaceutically and veterinarily acceptable acid addition salts or hydrates thereof. The present invention is further directed to pharmaceutical and veterinary compositions containing the compounds of general formula I. The present compounds of general formula I are antagonist of platelet activating factor (PAF). Accordingly, the present invention is also directed to methods for preventing, treating or ameliorating in human or mammalian animals, various diseases or physiological conditions mediated by PAF.
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Inventors:
Bowls, stephan, arthur
Mirror, Andrew
Whittaker, mark
Mirror, Andrew
Whittaker, mark
Application Number:
JP51389993A
Publication Date:
April 27, 1995
Filing Date:
February 10, 1993
Export Citation:
Assignee:
British Bio-Technology Limited
International Classes:
A61K31/435; A61P1/00; A61P9/00; A61P9/12; A61P11/00; A61P43/00; C07C311/15; C07C311/19; C07D207/335; C07D209/14; C07D213/74; C07D239/48; C07D271/06; C07D271/10; C07D277/64; C07D277/82; C07D285/12; C07D285/135; C07D307/14; C07D295/20; C07D307/52; C07D307/68; C07D333/16; C07D333/20; C07D333/34; C07D471/04; C07F9/6561; (IPC1-7): C07D471/04; A61K31/435; C07C311/15; C07D207/335; C07D209/14; C07D213/74; C07D239/48; C07D271/06; C07D271/10; C07D277/82; C07D285/135; C07D295/20; C07D307/14; C07D307/52; C07D307/68; C07D333/16; C07D333/20; C07D333/34; C07F9/6561
Attorney, Agent or Firm:
Shintaro Nogawa