Title:
【発明の名称】ボンベシンのフェニルアラニン類似体類
Document Type and Number:
Japanese Patent JPH07505865
Kind Code:
A
Abstract:
Disclosed are Agonists and Antagonists of bombesin which are derivatives of naturally occurring bombesin possessing modified derivatives of phenylalanine. Agonist and antagonist activities are confirmed using conventional competitive binding and biochemical assays as well as conventional physiological tests and the use of these derivatives in a variety of conditions. Use of these peptides may be useful for stimulating or antagonising growth of tissues, especially lung, and of digestion. Treatment comprises administering to a patient in need thereof, an effective amount of a bombesin analog.
Inventors:
Edwards, Judson Vee.
Funger, Bradford Oh.
Funger, Bradford Oh.
Application Number:
JP51325093A
Publication Date:
June 29, 1995
Filing Date:
January 07, 1993
Export Citation:
Assignee:
Merrell Dow Pharmaceuticals Inc.
International Classes:
A61P1/14; A61P3/04; A61P43/00; A61K38/00; C07K1/04; C07K7/08; C07K14/575; (IPC1-7): C07K7/08; A61K38/00; C07K1/04
Attorney, Agent or Firm:
Katsuro Sasai