Title:
【発明の名称】DNA損傷因子に対する細胞の感受性を増強する方法および組成物
Document Type and Number:
Japanese Patent JPH08501205
Kind Code:
A
Abstract:
The invention provides a method of increasing the sensitivity of a cell to a DNA damaging agent comprising increasing the amount of an NM23 in the cell. The method is especially useful for increasing the sensitivity of tumor cells to chemotherapy and radiation.
Inventors:
Stig, Patricia S.
Riotta, Lance A.
Flatow, Ursula
Chew, gilbert
Riotta, Lance A.
Flatow, Ursula
Chew, gilbert
Application Number:
JP50094194A
Publication Date:
February 13, 1996
Filing Date:
May 20, 1993
Export Citation:
Assignee:
The Government of the United States of America, As Represented by the Secretary, Department of Health and Human Services
International Classes:
A61K31/70; A61K48/00; A61P35/00; A61P43/00; C12N5/10; C12N9/12; C12N15/09; G01N33/577; C12P21/02; C12Q1/02; (IPC1-7): C12N15/09; A61K31/70; C12N5/10; C12P21/02; C12Q1/02
Domestic Patent References:
| JPH02113533A | 1990-04-25 | |||
| JPS57138165A | 1982-08-26 | |||
| JPH02156835A | 1990-06-15 |
Attorney, Agent or Firm:
Shusaku Yamamoto