Title:
【発明の名称】RNAバイナリ・プローブとRNA向けRNAリガーゼを使用したRNAの診断検定法およびそのキット
Document Type and Number:
Japanese Patent JPH08505532
Kind Code:
A
Abstract:
There are provided nucleic acid hybridization assays for RNA targets using RNA binary probes and a protein that is an RNA-directed RNA ligase. Preferred assays include generation of an exponentially amplified signal. Most preferred assays include T4 DNA ligase as the RNA-directed RNA ligase. Also provided are kits for performing assays according to this invention.
Inventors:
Taiagi, Sanjay
Application Number:
JP51632694A
Publication Date:
June 18, 1996
Filing Date:
January 14, 1994
Export Citation:
Assignee:
The Public Health Research Institute of the City of New York, Inc.
International Classes:
C07H21/02; C12Q1/68; C12Q1/6862; C12N15/09; C12Q1/6867; (IPC1-7): C12Q1/68; C07H21/02; C12N15/09
Attorney, Agent or Firm:
Masatake Shiga (2 outside)