Title:
【発明の名称】アシル化タンパク質凝集物、ならびに抗体に対するイムノアッセイ試験での信号増強へのその使用
Document Type and Number:
Japanese Patent JPH08506837
Kind Code:
A
Abstract:
PCT No. PCT/EP94/04265 Sec. 371 Date Feb. 29, 1996 Sec. 102(e) Date Feb. 29, 1996 PCT Filed Dec. 21, 1994 PCT Pub. No. WO95/17427 PCT Pub. Date Jun. 29, 1995The invention addresses protein aggregates that are acylated with -CO- R groups, wherein R is a branched or non-branched C1-C4 alkyl residue which can be substituted with hydroxy, carboxy, SO3H or PO3H2 groups. These protein aggregates can be used to increase the intensity of signals and avoid false-positive results in immunoassays for the detection of antibodies. The inventions also adresses a reagent with a buffer and a binding reagent with an immunological binding partner containing said protein aggregate.
Inventors:
Schmidt, Urban
Shree Pale, Dittmer
Schmid, Franz
Shree Pale, Dittmer
Schmid, Franz
Application Number:
JP51719695A
Publication Date:
July 23, 1996
Filing Date:
December 21, 1994
Export Citation:
Assignee:
Boehringer Mannheim Gaem Behr
International Classes:
C07K1/10; C07K1/107; C07K14/765; C07K19/00; G01N33/53; G01N33/531; G01N33/543; (IPC1-7): C07K14/765; C07K1/107; C07K19/00; G01N33/531
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)