Title:
【発明の名称】組換えC140受容体ならびにそのアゴニストおよびアンタゴニスト
Document Type and Number:
Japanese Patent JPH09503906
Kind Code:
A
Abstract:
The DNA encoding the C140 cell surface receptor has been cloned and sequenced. The availability of this DNA permits the recombinant production of the C140 receptor which can be produced at cell or oocyte surfaces and is useful in assay systems both for the detection of substances which affect its activity, including agonists and antagonists. Further, the elucidation of the structure of the C140 receptor permits the design of agonist and antagonist compounds which are useful in these assays. The availability of the C140 receptor also permits production of antibodies specifically immunoreactive with the receptor per se or with specific regions thereof.
Inventors:
Scarborough, Robert M
Sunderin, Johann
Sunderin, Johann
Application Number:
JP50540894A
Publication Date:
April 22, 1997
Filing Date:
July 26, 1994
Export Citation:
Assignee:
COR Therapeutics Incorporated
International Classes:
C12N15/09; C07H21/04; C07K7/06; C07K7/08; C07K14/705; C07K14/72; C07K16/28; C12N5/10; C12P21/02; A61K38/00; A61K48/00; C12R1/91; (IPC1-7): C12N15/09; C07H21/04; C07K7/06; C07K7/08; C07K14/705; C07K16/28; C12N5/10; C12P21/02
Attorney, Agent or Firm:
Kyozo Yuasa (6 people outside)