Title:
バクテリアによって誘発される炎症性疾患の治療
Document Type and Number:
Japanese Patent JPH09511220
Kind Code:
A
Abstract:
The lipopolysaccharide of bacteria associated with chronic inflammatory diseases is unable to induce expression of leukocyte adhesion molecules, or selectins, on endothelial cells, and is also capable of inhibiting the induction of selectin expression by bacteria normally associated with acute endotoxin disease. New approaches to treatment of these diseases, and the diagnosis of susceptibility to chronic bacterial-associated inflammatory diseases, are provided.
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Inventors:
ダーヴィーユ リチャード ピー
Application Number:
JP51402495A
Publication Date:
November 11, 1997
Filing Date:
November 10, 1994
Export Citation:
Assignee:
ブリストル‐マイヤーズ スクイブ カンパニー
International Classes:
A61K8/66; A61K8/99; A61K35/74; A61K8/00; A61K38/46; A61K39/395; A61P31/04; A61Q11/00; C07K16/12; C12Q1/18; G01N33/50; (IPC1-7): A61K39/395; A61K7/16; A61K38/46
Attorney, Agent or Firm:
中村 稔 (外6名)