Title:
【発明の名称】自己免疫疾患に関連する自己及び非自己抗原の同定
Document Type and Number:
Japanese Patent JPH10500705
Kind Code:
A
Abstract:
The present invention provides isolated peptides relating to the autoimmune diseases pemphigus vulgaris and multiple sclerosis. The peptides relating to pemphigus vulgaris are self epitopes and those relating to multiple sclerosis are foreign antigens derived from human pathogens which are implicated in the aetiology and remissions of the disease. Pharmaceutical preparations for tolerizing and/or immunizing individuals are provided as well as methods relating thereto. Methods are provided for identifying other self and non-self epitopes involved in human autoimmune disease and similar pharmaceutical preparations and methods of use for these epitopes are also provided.
Inventors:
Stromminger, Jack El.
Buscher Fenig, Kai We.
Buscher Fenig, Kai We.
Application Number:
JP52706496A
Publication Date:
January 20, 1998
Filing Date:
March 07, 1996
Export Citation:
Assignee:
President and Fellows of Harvard College
International Classes:
G01N33/53; A61K38/00; A61K39/104; A61K39/145; A61K39/15; A61K39/235; A61K39/245; A61P25/00; A61P37/00; C07K7/08; C07K14/11; C07K14/14; C07K14/47; C07K14/74; G01N33/564; A61K39/00; (IPC1-7): C07K7/08; A61K38/00; A61K39/104; A61K39/145; A61K39/15; A61K39/235; A61K39/245; C07K14/11; C07K14/14; C07K14/74; G01N33/53; G01N33/564
Attorney, Agent or Firm:
Kiyoya Fujino (1 outside)