Title:
【発明の名称】シクロスポリンAの製造方法
Document Type and Number:
Japanese Patent JPH10507355
Kind Code:
A
Abstract:
PCT No. PCT/KR95/00095 Sec. 371 Date Jun. 16, 1997 Sec. 102(e) Date Jun. 16, 1997 PCT Filed Jul. 31, 1995 PCT Pub. No. WO96/12031 PCT Pub. Date Apr. 25, 1996A process for the isolation of cyclosporin A comprising the steps of: adding a lower alkanol solvent to a culture fluid of a mutant of Tolypocladium inflatum to form a mixture, filtering the mixture to form an extract, transferring the extract to methylene chloride as a solvent therefor, and column chromatographing the resultant product on silica gel.
Inventors:
Kim, Jung, Wu
Choi, Nam, Hee
Lee, sang, tulle
Choi, Gang, Sun
Ham, Yun, Veom
Lee, Don, Wa
Min, Cheong, I
Choi, Nam, Hee
Lee, sang, tulle
Choi, Gang, Sun
Ham, Yun, Veom
Lee, Don, Wa
Min, Cheong, I
Application Number:
JP51310995A
Publication Date:
July 21, 1998
Filing Date:
July 31, 1995
Export Citation:
Assignee:
Chong Kung Dang Sea Ouarpie.
International Classes:
C12P35/06; A61K38/00; A61P37/06; C07K1/14; C07K1/16; C07K7/64; C12P21/04; C12R1/645; (IPC1-7): C12P21/04; C07K1/14; C07K1/16
Attorney, Agent or Firm:
Shunichiro Suzuki