Title:
【発明の名称】不安を治療する方法
Document Type and Number:
Japanese Patent JPH10508029
Kind Code:
A
Abstract:
Treating anxiety comprises admin. of a cpd. selected from about 150 specific cpds. e.g. 3-(3-Q-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methyl pyridine (I), 3-(3-X-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-ethylpyridine, 3-Y-1,2,5-thiadiazol-4-yl-1,2,5,6-tetrahydro-1-methyl pyridine, 3(3-1,2,5-thiadiazol-4-yl)-1-azabicyclo(2.2.2)octane 1-methyl-1,2,5,6-tetrahydro-3-Qa-1,2,5-thiadiazol-3-yl)-pyridine, 1,2,5,6-tetrahydro-1-methyl-3-(Qb-1,2,5-thiadiazol-3-yl)-pyridine, 3-(4-(1-ethylbutoxy or penhyloxy)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methyl pyridine, W = Cl, OBu Y = 2-ethoxyethoxy, 4-isohexyloxy Z = Cl, OEt, OPr, butylthio, pentylthio, OBu, propylthio, ethylthio, butylthio, isopentyloxy Qa = (4cyclopenyl propyl)oxy), 4-isoheptyloxy, 4-(3-methylpentyloxy) Qb = 4(2-methylbutoxy), 4-(2,2,2-trifluoroethoxy), 4(2-methylpentyloxy), 4-(2-methylbutoxy), 4-(1-methylpentyloxy, 4-(2-methylhexyloxy Q = 1-8C alkoxy, cyclopropylmethoxy, 3-butenoxy, but-2-ynoxy, 3-methylbutoxy, prop-2-ynoxy, benzyloxy, Cl, methoxyethoxy, 3-pentynyloxy, 4-pentenyloxy, 2-propenyloxy 3-hexynyloxy, 3-butenyl-2-oxy 2,3 4 or 5-hexenyloxy, 2-pentenyloxy, morpholino etc.
More Like This:
Inventors:
Bodick, Neil Clayton
Bimaster, Franklin Porter
Offen, Walter William
Shannon, Harlan Edgar
Bimaster, Franklin Porter
Offen, Walter William
Shannon, Harlan Edgar
Application Number:
JP51481295A
Publication Date:
August 04, 1998
Filing Date:
October 30, 1995
Export Citation:
Assignee:
ELI LILLY AND COMPANY
International Classes:
A61K31/435; A61K31/439; A61K31/44; A61K31/4439; A61K31/444; C07D417/04; A61K31/4545; A61K31/46; A61K31/5377; A61K31/55; A61P25/20; C07D453/02; C07D471/08; (IPC1-7): A61K31/44; A61K31/435; C07D417/04; C07D453/02; C07D471/08
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)