Title:
【発明の名称】アリールチオキサンチン類
Document Type and Number:
Japanese Patent JPH10508032
Kind Code:
A
Abstract:
Disclosed are compounds having formula (II):wherein: Q3, Q6a, Q6b and Q8 are independently a bond, C1-8 alkylene, C2-8 alkenylene and C2-8 alkynylene, and R3, R6a, R6b and R8 are independently hydrogen, aryl or heteroraryl, optionally substituted by halogen, hydroxy, alkoxy, nitro, cyano and carboxy, provided that: Q3R3 is not hydrogen or methyl. The compounds are effective PDE IV inhibitors and possess improved PDE IV inhibition and improved selectivity with regard to PDE III inhibition.
Inventors:
Kavala, David Jay.
Hofer, peter
Chaisin mark
Hofer, peter
Chaisin mark
Application Number:
JP51932696A
Publication Date:
August 04, 1998
Filing Date:
December 12, 1995
Export Citation:
Assignee:
Euro-Celtique, S.A.
International Classes:
A61K31/52; A61K31/522; A61P11/06; A61P25/24; A61P25/26; A61P25/28; A61P29/00; A61P37/08; A61P43/00; C07D473/18; C07D473/22; (IPC1-7): C07D473/22; A61K31/52; C07D473/18
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)