Title:
【発明の名称】抗癌剤
Document Type and Number:
Japanese Patent JPH10509957
Kind Code:
A
Abstract:
A method of treatment or inhibition of tumors involves administering a compound to a subject. The compound is one in which one or more of the eight phenyl substituents in the compound [M(dppe)2]+, in which M is selected from Au(I), Ag(I) and Cu(I), is substituted by 2, 3, or 4 pyridyl substituents. The compound has anti-tumor activity and an octanol/water partition coefficient between 0.01 and 25.5. The compound has selective toxicity to cancer cells, including cisplatin resistant human carcinoma cells lines.
Inventors:
Berners-Price, Susan Jane
Richard John Bowen
Parsons, Peter Gordon
Richard John Bowen
Parsons, Peter Gordon
Application Number:
JP51720495A
Publication Date:
September 29, 1998
Filing Date:
December 11, 1995
Export Citation:
Assignee:
Griffith University
International Classes:
A61K31/695; A61K31/675; A61P35/00; C07F9/50; C07F9/58; (IPC1-7): C07F9/50; A61K31/695
Attorney, Agent or Firm:
Tadahiko Ito (1 outside)