Title:
【発明の名称】アシル化インシュリン類似体
Document Type and Number:
Japanese Patent JPH10511644
Kind Code:
A
Abstract:
The present invention relates to the field of diabetes. More particularly, the invention relates to a monomeric insulin analog wherein the A chain is the naturally occurring sequence of the human insulin A chain and the B chain is modified at either position B28 and B29 or both. The analog is mono-acylated at the N-terminal of the A chain or B chain or at the lysine. The acylated insulin analogs have an extended duration of action.
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Inventors:
Baker, Jeffrey Clayton
Hank Wire, George Michael
Hank Wire, George Michael
Application Number:
JP51696496A
Publication Date:
November 10, 1998
Filing Date:
November 14, 1995
Export Citation:
Assignee:
ELI LILLY AND COMPANY
International Classes:
A61K38/28; A61P3/08; C12N15/09; A61P5/38; C07K14/62; G01N33/68; A61K38/00; (IPC1-7): C07K14/62; A61K38/28
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)