Title:
【発明の名称】指数濃縮によるリガンドの体系的進化:ケミセレックス
Document Type and Number:
Japanese Patent JPH11502105
Kind Code:
A
Abstract:
This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
Inventors:
Gold, rally
Eaton, Bruce
Smith, Drew
Wecker, Matthew
Jensen, Kirk
Eaton, Bruce
Smith, Drew
Wecker, Matthew
Jensen, Kirk
Application Number:
JP52703796A
Publication Date:
February 23, 1999
Filing Date:
March 05, 1996
Export Citation:
Assignee:
Nexter Pharmaceuticals, Inc.
International Classes:
C07H19/06; C07H19/10; C07H21/00; G01N33/58; C07K14/00; C12N9/12; C12N15/09; C12N15/10; C12N15/115; C12Q1/37; C12Q1/68; C12Q1/70; G01N33/531; G01N33/532; G01N33/535; G01N33/569; G01N33/68; G01N33/76; C07B61/00; F02B75/02; (IPC1-7): C12Q1/68; C12N15/09; G01N33/58
Attorney, Agent or Firm:
Akira Asamura (3 outside)