Title:
【発明の名称】非ステロイド性スルファターゼ阻害剤化合物及びその製法
Document Type and Number:
Japanese Patent JPH11510813
Kind Code:
A
Abstract:
This invention discloses compounds useful as non-steroidal sulfatase inhibitors. The compounds comprise the formula (1) (1) wherein (a) R1 is selected from the group consisting of hydrogen and a lower alkyl group, (b) R2 is selected from the group consisting of H and a lower alkyl group, (c) m is an integer from 0 to 4, and (d) n is an integer from 5 to 14. R1 is selected from the group consisting of H and C1-C6 alkyl and R2 is selected from the group consisting of H and C1-C6 alkyl. The invention also discloses methods of treating a patient prophylactically to provide protection as an estrogen depleting agent for estrogen dependent illnesses and treating a patient therapeutically for estrogen dependent diseases. A method of making the non-steroidal sulfatase inhibitors is also disclosed.
Inventors:
Lee, Pui-Kai
Application Number:
JP50946897A
Publication Date:
September 21, 1999
Filing Date:
August 15, 1996
Export Citation:
Assignee:
Dokane University of the Holy Ghost
International Classes:
A61K31/165; A61K31/18; A61P5/32; A61P15/00; A61K31/00; A61P35/00; C07C303/34; C07C307/02; (IPC1-7): C07C307/02; A61K31/00; A61K31/165; C07C303/34
Attorney, Agent or Firm:
Toshiyuki Maruyama (1 outside)