Document Type and Number:
Japanese Patent JPS4946623
Kind Code:
B1
Abstract:
1,256,354. Bis-chromones. FISONS PHARMACEUTICALS Ltd. 22 April, 1969 [16 Feb., 1968], No. 7590/68. Heading C2C. Compounds of formula and their functional derivatives, are prepared by reacting a compound of formula with a compound of formula and where necessary converting the pairs of groups A 1 , As to -COCH=C(CO 2 H)-O- or a functional derivative thereof. In the formulµ, X is a carboxylic or heterocyclic ring, or an acyclic chain, which ring or chain may be interrupted by one or more heterocyclic or carbocyclic rings, by >C=O, O, S, NH, or by substituted S or NH; P, Q, T, P1 , Q1 , T1 are each H, halogen or optionally substituted alkyl or alkoxy; L1 , L2 are groups capable of forming an X group; the pair of groups A1 , A2 is (being not necessarily identical on each ring) OM and H or COJ, H and OCD=CHOO 2 R2 , OCOCOR3 and H or COCH 3 , or together form the chain COCH=C(D)-O- or COCH 2 CH(D)-O-; M is H, alkali metal or C 1-6 alkyl; J is CH 3, OR2 , CH 2 COD or CH = CHD; R2 is H or C 1-10 alkyl, D is CO 2 R2 or a group convertible thereto and R3 is OH or a group convertible thereto. Details are given for the preparation of ethyl 5 - (2 - chloroethoxy)chromone - 2 - carboxylate and the iodoethoxy analogue.
Application Number:
JP11063170A
Publication Date:
December 11, 1974
Filing Date:
December 14, 1970
Export Citation:
International Classes:
C07D311/24; (IPC1-7): C07D7/34