Document Type and Number:
Japanese Patent JPS5737589
Kind Code:
B2
Abstract:
Anti-ulcer agents of the formula I wherein R1 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive, are prepared by reacting a compound of the formula II wherein X is a conventional leaving group, preferably in the form of its acid addition salt, with a compound of the formula III wherein R1 is as defined above. The intermediates of Formula III may be prepared by reacting a cysteamine salt with an isothiourea of the formula V wherein R1 is as described above, in the presence of a base.
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Application Number:
JP3482980A
Publication Date:
August 10, 1982
Filing Date:
March 21, 1980
Export Citation:
International Classes:
C07C335/38; A61K31/415; A61P1/00; A61P1/04; C07C67/00; C07C313/00; C07C323/44; C07C325/00; C07D233/54; C07D233/64; C07D277/64