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Title:
BIS-N,N'-(3-BENZYLOXY-2-NITRO-4-SUBSTITUTED-BENZOYL) ALKYLDIAMINE DERIVATIVE AND ITS PREPARATION
Document Type and Number:
Japanese Patent JPS58144356
Kind Code:
A
Abstract:

NEW MATERIAL:The compound of formulaI(n is even number of 2W12; R is H or lower alkyl).

EXAMPLE: Bis-N,N'-(3-benzyloxy-4-methyl-2-nitrobenzoyl)ethylenediamine.

USE: An intermediate of a novel crosslinked phenoxazine which is expected to have antitumor activity.

PROCESS: The compound of formulaIcan be prepared by reacting 3-(benzyloxy)- 2-nitro-4-substituted benzoic acid with phosphorus pentachloride, and reacting the resultant 3-(benzyloxy)-2-nitro-4-substituted-benzoyl chloride with an alkylenediamine or alkylenediamine dihydrochloride of formula H2N-(CH2)n-NH2 or H2N-(CH2)n-NH2.2HCl.


Inventors:
MOTOHASHI NOBORU
Application Number:
JP2598082A
Publication Date:
August 27, 1983
Filing Date:
February 22, 1982
Export Citation:
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Assignee:
MOTOHASHI NOBORU
International Classes:
C07C235/50; (IPC1-7): C07C103/85
Attorney, Agent or Firm:
Yukio Adachi