Title:
【発明の名称】天然プロスタグランジン及びプロスタグランジンの合成類縁体の精製法
Document Type and Number:
Japanese Patent JPS5835992
Kind Code:
B2
Abstract:
Prostanoic acid esters of the formula PG - CH2 - X - Y wherein PG is the prostanoyloxy radical of a prostaglandin, X is a carbon-carbon single bond, carbonyl or carbonyloxy, and Y is substituted phenyl are easily crystallized compounds at least as active as the unesterified prostanoic acid and useful for the purification of the parent prostaglandin are prepared by reacting, in the presence of an agent which splits off hydrogen halide, the unesterified prostaglandin with a halide of the formula Hal-CH2-X-Y, wherein Hal is a halogen atom and X and Y have the values given above.
Inventors:
BERUNERU SUKURABA
BERUNTO RAADEYUHIERU
HERUMUUTO FUORUBURYUTSUGEN
BARUTERU ERUGERU
ORAAFU ROOGE
BORUFUGANGU ROOZERUTO
BERUNTO RAADEYUHIERU
HERUMUUTO FUORUBURYUTSUGEN
BARUTERU ERUGERU
ORAAFU ROOGE
BORUFUGANGU ROOZERUTO
Application Number:
JP4704782A
Publication Date:
August 05, 1983
Filing Date:
March 24, 1982
Export Citation:
Assignee:
SCHERING AG
International Classes:
A61K31/557; A61K31/5575; C07C67/00; C07C401/00; C07C405/00; (IPC1-7): C07C177/00
Attorney, Agent or Firm:
Toshio Yano