Title:
MACROLIDE ANTIBIOTIC
Document Type and Number:
Japanese Patent JPS5874695
Kind Code:
A
Abstract:
NEW MATERIAL:Spiramycin U and spiramycin S shown by the formula (R is formyl or hydroxymethyl) having the following properties. White and slightly basic; values of elemental analysis: H 8.31, C 59.99, and N 1.43; molecular weight: 845; melting point: 138W141°C; specific rotatory power:[α]23D=-115(C 1.0 methanol).
USE: An antibacterial agent for Gram-positive bacteria.
PROCESS: A bacterium such as Streptomyces ambofaciens NRRL 2420 belonging to the genus Streptomyces is cultivated under aerobic conditions at 24W30°C at a pH of 6W8.
Inventors:
SHIRAHATA KIMIKATSU
SAITOU YUTAKA
SHIMAMURA ETSUKO
SAITOU YUTAKA
SHIMAMURA ETSUKO
Application Number:
JP17362281A
Publication Date:
May 06, 1983
Filing Date:
October 29, 1981
Export Citation:
Assignee:
KYOWA HAKKO KOGYO KK
International Classes:
C12P19/62; A61K31/70; A61K31/7042; A61K31/7048; A61P31/04; C07H17/08; C12R1/465; (IPC1-7): A61K31/71; C07H17/08; C12P19/62
Attorney, Agent or Firm:
Shunji Nonami