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Document Type and Number:
Japanese Patent JPS6244560
Kind Code:
B2
Abstract:
This specification relates to the production of 9.alpha.-halo-11.beta.-hydroxy-corticosteroids, to intermediates used in the production of such steroids, and to the production of such intermediates themselves. The specification is particularly concerned with the production of such steroids having anti-inflammatory action, e.g. beclomethasone dipropionate. There is disclosed a new route for preparing 9.alpha.halo-11.beta.-hydroxy-corticosteroids which involves the formation of novel 9.beta.,11.beta.-epoxy steroids which themselves may be conveniently obtained from the corresponding 9.alpha.-bromo-11.beta.-hydroxy-corticosteroids.

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Inventors:
HENRII REON REBINSUKII
HAUSHANGU TORABII
DAANII FURANSHISU MOROO
Application Number:
JP6287977A
Publication Date:
September 21, 1987
Filing Date:
May 31, 1977
Export Citation:
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Assignee:
BRISTOL MYERS CO
International Classes:
A61K31/57; A61K31/58; A61P29/00; C07J5/00; C07J21/00; C07J71/00



 
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