Title:
培地用高分子ゲル、培地、細胞の培養方法及びキット
Document Type and Number:
Japanese Patent JPWO2018021289
Kind Code:
A1
Abstract:
硬さを容易、かつ、可逆的に変化させることができ、しかも、その硬さに応じて細胞の形を制御させることを可能とする、培地用高分子ゲル及び培地、また、当該培地を使用した細胞の培養方法を提供する。培地用高分子ゲルは、可逆的結合によって架橋された架橋構造体と溶媒とを含む。培地用高分子ゲルは、硬さを容易、かつ、可逆的に変化させることができる。ゆえに、本発明に係る培地用高分子ゲルによれば、その硬さに応じて細胞の形および機能を可逆的に制御させることが可能である。
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Inventors:
Akira Harada
Takashima Yoshinori
Masaki Nakahata
Tanaka
Halling Marcel
Takashima Yoshinori
Masaki Nakahata
Tanaka
Halling Marcel
Application Number:
JP2018529902A
Publication Date:
May 09, 2019
Filing Date:
July 25, 2017
Export Citation:
Assignee:
National University Corporation Osaka University
Kyoto University
Kyoto University
International Classes:
C12M3/00; C08F8/00; C08F20/54; C12N1/00
Domestic Patent References:
| JP2013233101A | 2013-11-21 | |||
| JP2016103982A | 2016-06-09 | |||
| JP2006042795A | 2006-02-16 |
Foreign References:
| WO2012036069A1 | 2012-03-22 |
Other References:
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KAKUTA, T. ET AL.: "Adhesion between Semihard Polymer Materials Containing Cyclodextrin and Adamantane Based on Host-Gue", MACROMOLECULES, vol. 48, JPN6017038781, 2015, pages 732 - 738, XP055321951, ISSN: 0004486603, DOI: 10.1021/ma502316d
LAN, Y. ET AL.: "A supramolecular route towards core-shell polymeric microspheres in water via cucurbit[8]uril comple", CHEM. COMMUN., vol. 48, JPN6017038782, 2012, pages 8757 - 8759, ISSN: 0004486604
PATRA, D. ET AL.: "Formation and Size Tuning of Colloidal Microcapsules via Host-Guest Molecular Recognition at the Liq", LANGMUIR, vol. 25, no. 24, JPN6017038783, 2009, pages 13852 - 13854, XP055578416, ISSN: 0004486605, DOI: 10.1021/la9015756
MCKINNON, D.D. ET AL.: "Biophysically Defined and Cytocompatible Covalently Adaptable Networks as Viscoelastic 3D Cell Cultu", ADV. MATER., vol. 26, JPN6018013761, 2014, pages 865 - 872, ISSN: 0004486606
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office
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