1 and 4 -2 substitution 1, 2, and 3 - doria -- Orres and its preparing method -- and -- the -- diagnostic and therapeutic use - Center National de la Cherche Sientifique (Se en Els)

Title:

1 and 4 -2 substitution 1, 2, and 3 - doria -- Orres and its preparing method -- and -- the -- diagnostic and therapeutic use

Document Type and Number:

Japanese Patent JP5969004

Kind Code:

B2

Abstract:

A compound having the following general formula (I): wherein: X is a nitrogen atom and Y is a carbon atom; or X is a carbon atom and Y is a nitrogen atom; the Ar group is an aryl or heteroaryl group; and the RN and RN' groups, together with the carbon atoms to which they are bound, form a monocyclic or bicyclic azacycloalkane group. The pharmaceutically acceptable salts thereof, the hydrates or polymorphic crystalline structures thereof, and to the racemates, diastereoisomers, or enantiomers thereof are also described.

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Inventors:

Sylvain Routier
Frank Suzene
Frederick bread
Sylvie Sharon
Johnny Velquiury
Doni Guilloteau

Application Number:

JP2014505656A

Publication Date:

August 10, 2016

Filing Date:

April 20, 2012

Export Citation:

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Assignee:

Center National de la Cherche Sientifique (Se en Els)
Anstituto Nacional de la Sante et de la Le Chalche Medical (Inselm)

International Classes:

C07D451/04; C07D453/02; C07D455/02

Domestic Patent References:

JP2008524212A
JP2007511603A
JP2009504735A
JP2008524339A
JP2009533327A
JP2008517032A
JP2010535738A
JP2003514818A

Foreign References:

WO2006004142A1
WO1996021660A1
WO2009092293A1
WO2011025690A1
WO2010007966A1
WO2010015583A1
WO2008156580A1
WO2010071741A1

Attorney, Agent or Firm:

Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro

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