Title:
１−ヒドロキシイミノ−３−フェニル−プロパン類
Document Type and Number:
Japanese Patent JP5593445
Kind Code:
B2
Abstract:
This invention relates to novel 1-hydroxyimino-3-phenyl-propanes of the formula wherein R1 to R10 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and may be used as medicaments for the treatment of diseases such as type II diabetes.
Inventors:
ビサンツ, Yekaterina
A dame low, Henrietta
Ericsson, Sean David
Kim, キョンジン
Martin, Reiner Ey
Matthew, パトリツィオ
A オプスト zander, Ulrike
A ピエトラニコ * call, Cherylene
Richter, Hans
ウリマー, Christoff
A dame low, Henrietta
Ericsson, Sean David
Kim, キョンジン
Martin, Reiner Ey
Matthew, パトリツィオ
A オプスト zander, Ulrike
A ピエトラニコ * call, Cherylene
Richter, Hans
ウリマー, Christoff
Application Number:
JP2013519039A
Publication Date:
September 24, 2014
Filing Date:
July 08, 2011
Export Citation:
Assignee:
F. Hoffmann * ラ Roche アーゲー F. HOFFMANN*LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07C251/40; A61K31/15; A61K31/44; A61K31/4409; A61K31/4412; A61K31/4425; A61K31/4427; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/444; A61K31/4545; A61K31/496; A61K31/5377; A61K31/541; A61P1/04; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/12; A61P17/06; A61P19/02; A61P25/00; A61P25/18; A61P25/28; A61P27/02; A61P29/00; A61P37/08; A61P43/00; C07C249/08; C07D213/53; C07D401/06; C07D401/10; C07D401/12; C07D405/12; C07D409/10; C07D409/12; C07D413/10; C07D413/14; C07D417/06; C07D495/10
Attorney, Agent or Firm:
Patent business corporation Tsukuni
Hajime Tsukuni
Yasuo Yanagibashi
Ito 佐保子
Keiko Ozawa
Toshio Miyake
Yasuhiro Kokuni
Yoko Tanaka
Yoshinori Ubukawa
Akio Shibata
Hajime Tsukuni
Yasuo Yanagibashi
Ito 佐保子
Keiko Ozawa
Toshio Miyake
Yasuhiro Kokuni
Yoko Tanaka
Yoshinori Ubukawa
Akio Shibata