Title:
1-METHYL-15 ALPHA-(1-OXYALKYL)-ANDROST-1, 4-DIENE-3, 17-DIONE, ITS PRODUCTION AND ESTROGEN BIOSYNTHESIS INHIBITOR CONTAINING THE SAME
Document Type and Number:
Japanese Patent JPS63222196
Kind Code:
A
Abstract:
1-Methyl-15 alpha -(1-oxyalkyl)androsta-1,4-diene-3,17-diones of general Formula I (I) wherein R1 is a hydrogen atom or an acyl group of 1-10 carbon atoms, R2 is an OR4, NHR5 or an S(O)nR6 group, R4 being straight- or branched-chain alkyl group of 1-10 carbon atoms, R5 being an acyl group of 1-10 carbon atoms, R6 being a straight- or branched-chain alkyl group of 1-10 carbon atoms or an aryl group of 6-10 carbon atoms, R3 is a hydrogen atom or a straight- or branched-chain alkyl group of 1-8 carbon atoms, and n is 0, 1 or 2, are suitable as inhibitors of estrogen biosynthesis for fertility control and for the treatment of diseases that are evoked by estrogens.
Inventors:
URURIHI KERUPU
NISHINO YUKISHIGE
DEBUITSUDO HENDAASON
NISHINO YUKISHIGE
DEBUITSUDO HENDAASON
Application Number:
JP3544188A
Publication Date:
September 16, 1988
Filing Date:
February 19, 1988
Export Citation:
Assignee:
SCHERING AG
International Classes:
C07J1/00; C07J17/00; C07J31/00; C07J41/00; A61K31/565; (IPC1-7): A61K31/565; C07J1/00; C07J31/00; C07J41/00
Attorney, Agent or Firm:
Toshio Yano (1 outside)
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