Title:
II型糖尿病の処置用の11-β-ヒドロキシステロイド・デヒドロゲナーゼのインヒビターとしての1-スルホニル-ピペリジン-3-カルボン酸アミド誘導体
Document Type and Number:
Japanese Patent JP2008531616
Kind Code:
A
Abstract:
Provided herein are compounds of the formula (1): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
Inventors:
Gillespie, Paul
Goodnow, Robert Alan Jr.
Kovarchik, Anieshka
Seo, Sung-Saw
Tsang, Chang
Goodnow, Robert Alan Jr.
Kovarchik, Anieshka
Seo, Sung-Saw
Tsang, Chang
Application Number:
JP2007557372A
Publication Date:
August 14, 2008
Filing Date:
February 22, 2006
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D211/96; A61K31/445; A61K31/4535; A61K31/454; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/5377; A61K31/538; A61K31/55; A61P3/00; A61P3/10; A61P43/00; C07D401/06; C07D409/12; C07D409/14; C07D413/12; C07D413/14; C07D487/08
Domestic Patent References:
| JP2008504275A | 2008-02-14 | |||
| JP2008504274A | 2008-02-14 |
Foreign References:
| WO2004033427A1 | 2004-04-22 | |||
| WO2005113542A2 | 2005-12-01 | |||
| WO2004089416A2 | 2004-10-21 |
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito