Title:
1,1-DIOXOPENICILLANOYL OXYMETHYL D-6-(ALPHA-(METHYLENEAMINO) PHENYLACETAMIDO)-PENICILLANATE AND ITS SALT, PREPARATION THEREOF AND REMEDY FOR BACTERIAL INFECTION THEREFROM
Document Type and Number:
Japanese Patent JPH0331289
Kind Code:
A
Abstract:
NEW MATERIAL: Compounds given by formula I.
USE: Remedy for bacterial infections.
PROCESS: An iodomethyl derivative of sulbactam, 3,3-dimethyl-7-oxo-4-thia-1- azabicyclo(3,2,0)heptane-2-carboxylic acid, 4,4-dioxide[2S(2α.5α)] is reacted with methanepicilin,6-[D(-)-α-(methylamino)phenylacetamido]penicillanic acid (salt) of formula III (wherein M is H, ammonium or an alkali metal) in the presence of a solvent (preferably DMF) preferably at -5-5°C for 3-24 hr.
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Inventors:
YON SURU KIMU
Application Number:
JP16003490A
Publication Date:
February 12, 1991
Filing Date:
June 20, 1990
Export Citation:
Assignee:
YON SURU KIMU
International Classes:
C07D499/68; A61K31/43; A61P31/04; C07D499/28; C07D499/86; C07D519/00; C07D519/06; (IPC1-7): A61K31/43; C07D499/68; C07D519/00
Attorney, Agent or Firm:
Hajime Tsukuni (1 person outside)
Next Patent: PRODUCTION OF TERTIARY HYDROCARBON SILYL COMPOUND