１，２，４−トリアジン−６−カルボキサミド誘導体

Japanese Patent JP5878178

B2

The present invention provides a compound represented by the following general formula (I) or a salt thereof which has a Syk inhibitory effect (in the formula R 1 represents a hydrogen atom or an optionally R a -substituted C 1 -C 6 alkyl group; A represents a hydrogen atom, an optionally R a -substituted C 1 -C 8 alkyl group, an optionally R a -substituted C 2 -C 6 alkenyl group, an optionally R a -substituted C 2 -C 6 alkynyl group, an optionally R b -substituted C 3 -C 10 cycloalkyl group, an optionally R b -substituted C 6 -C 14 aromatic hydrocarbon group, an optionally R b -substituted 4- to 10-membered unsaturated heterocyclic group, or an optionally R b -substituted 4-to 10-membered saturated heterocyclic group, or optionally forms a 4- to 10-membered unsaturated heterocyclic ring or a 4- to 10-membered saturated heterocyclic ring together with R 1 and the nitrogen atom bonded thereto; R 2 represents a hydrogen atom or an optionally R a -substituted C 1 -C 6 alkyl group; and B represents an optionally R c -substituted unsaturated heterocyclic group).

Toshihiro Sakamoto
Takashi Mita
Kazuro Shibata
Etsuo Ogino
Hideya Komatani

JP2013536457A

March 08, 2016

September 28, 2012

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Taiho Pharmaceutical Co., Ltd.

C07D401/12; A61K31/53; A61P35/00; A61P43/00; C07D401/14; C07D403/12; C07D403/14; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D413/12; C07D417/12; C07D471/04; C07D495/04

WO2000075113A1
WO1999031073A1
WO2000076980A1

Alga Patent Office, a patent business corporation
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto

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